UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, DC 20549

 

SCHEDULE 13D

Under the Securities Exchange Act of 1934

 

(Amendment No. 1)*

 

ERYTECH Pharma S.A.

 

(Name of Issuer)

 

Ordinary Shares, nominal value €0.10 per share

 

(Title of Class of Securities)

 

29604W108

 

(CUSIP number)

 

Alexandra A. Toohey

Chief Financial Officer

Baker Bros. Advisors LP

860 Washington Street, 3rd Floor

New York, NY 10014

(212) 339-5690

 

(Name, address and telephone number of person authorized to receive notices and communications)

 

June 28, 2018

 

(Date of event which requires filing of this statement)

 

If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of Rule 13d-1(e), 13d-1(f) or 13d-1(g), check the following box. ¨

 

(Continued on the following pages)

 

 

 

Note: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See Rule 13d-7 for other parties to whom copies are to be sent.

 

* The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

 

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

 

 

 

 

CUSIP No.  29604W108   Page   2   of   9   Pages

 

 

1.

NAMES OF REPORTING PERSONS

 

Baker Bros. Advisors LP

2.

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

(a) ¨

(b) ¨

3.

SEC USE ONLY

 

 

4.

SOURCE OF FUNDS*

 

OO

5.

CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) or 2(e)

 

¨

6.

CITIZENSHIP OR PLACE OF ORGANIZATION

 

Delaware

NUMBER
OF SHARES
BENEFICIALLY
OWNED
BY EACH
REPORTING
PERSON WITH
7.

SOLE VOTING POWER

 

3,085,969 (1)

8.

SHARED VOTING POWER:

 

0

9.

SOLE DISPOSITIVE POWER:

 

3,085,969 (1)

10.

SHARED DISPOSITIVE POWER:

 

0

11.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:

 

3,085,969 (1)

12.

CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*

 

¨

13.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

 

17.2% (1)(2)

14.

TYPE OF REPORTING PERSON*

 

IA, PN

 

(1)

Includes 1,085,969 of the Ordinary Shares of ERYTECH Pharma S.A. (the “Issuer”) that are beneficially owned through American Depositary Shares (“ADS”). Each ADS represents 1 Ordinary Shares of the Issuer.

 

(2)Based on 17,940,035 Ordinary Shares outstanding as of May 31, 2018 as reported by the Issuer.

 

 

 

CUSIP No.  29604W108   Page   3   of   9   Pages

 

 

1.

NAMES OF REPORTING PERSONS

 

Baker Bros. Advisors (GP) LLC

2.

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

(a) ¨

(b) ¨

3.

SEC USE ONLY

 

 

4.

SOURCE OF FUNDS*

 

OO

5.

CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) or 2(e)

 

¨

6.

CITIZENSHIP OR PLACE OF ORGANIZATION

 

Delaware

NUMBER
OF SHARES
BENEFICIALLY
OWNED
BY EACH
REPORTING
PERSON WITH
7.

SOLE VOTING POWER:

 

3,085,969 (1)

8.

SHARED VOTING POWER:

 

0

9.

SOLE DISPOSITIVE POWER:

 

3,085,969 (1)

10.

SHARED DISPOSITIVE POWER:

 

0

11.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:

 

3,085,969 (1)

12.

CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*

 

¨

13.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

 

17.2% (1)(2)

14.

TYPE OF REPORTING PERSON*

 

HC, OO

 

(1)Includes 1,085,969 of the Ordinary Shares of the Issuer that are beneficially owned through ADS. Each ADS represents 1 Ordinary Shares of the Issuer.

 

(2)Based on 17,940,035 Ordinary Shares outstanding as of May 31, 2018 as reported by the Issuer.

 

 

 

CUSIP No.  29604W108   Page   4   of   9   Pages

 

 

1.

NAMES OF REPORTING PERSONS

 

Julian C. Baker

2.

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

(a) ¨

(b) ¨

3.

SEC USE ONLY

 

 

4.

SOURCE OF FUNDS*

 

OO

5.

CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) or 2(e)

 

¨

6.

CITIZENSHIP OR PLACE OF ORGANIZATION

 

United States

NUMBER
OF SHARES
BENEFICIALLY
OWNED
BY EACH
REPORTING
PERSON WITH
7.

SOLE VOTING POWER:

 

3,085,969 (1)

8.

SHARED VOTING POWER:

 

0

9.

SOLE DISPOSITIVE POWER:

 

3,085,969 (1)

10.

SHARED DISPOSITIVE POWER:

 

0

11.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:

 

3,085,969 (1)

12.

CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*

 

¨

13.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

 

17.2% (1)(2)

14.

TYPE OF REPORTING PERSON*

 

IN, HC

 

(1)Includes 1,085,969 of the Ordinary Shares of the Issuer that are beneficially owned through ADS. Each ADS represents 1 Ordinary Shares of the Issuer.

 

(2)Based on 17,940,035 Ordinary Shares outstanding as of May 31, 2018 as reported by the Issuer.

 

 

 

CUSIP No.  29604W108   Page   5   of   9   Pages

 

 

1.

NAMES OF REPORTING PERSONS

 

Felix J. Baker

2.

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

(a) ¨

(b) ¨

3.

SEC USE ONLY

 

 

4.

SOURCE OF FUNDS*

 

OO

5.

CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) or 2(e)

 

¨

6.

CITIZENSHIP OR PLACE OF ORGANIZATION

 

United States

NUMBER
OF SHARES
BENEFICIALLY
OWNED
BY EACH
REPORTING
PERSON WITH
7.

SOLE VOTING POWER:

 

3,085,969 (1)

8.

SHARED VOTING POWER:

 

0

9.

SOLE DISPOSITIVE POWER:

 

3,085,969 (1)

10.

SHARED DISPOSITIVE POWER:

 

0

11.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:

 

3,085,969 (1)

12.

CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*

 

¨

13.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

 

17.2% (1)(2)

14.

TYPE OF REPORTING PERSON*

 

IN, HC

 

(1)Includes 1,085,969 of the Ordinary Shares of the Issuer that are beneficially owned through ADS. Each ADS represents 1 Ordinary Shares of the Issuer.

 

(2)Based on 17,940,035 Ordinary Shares outstanding as of May 31, 2018 as reported by the Issuer.

 

 

 

CUSIP No.  29604W108   Page   6   of   9   Pages

 

 

Amendment No. 1 to Schedule 13D

 

This Amendment No. 1 to Schedule 13D amends and supplements the previously filed Schedule 13D filed by Baker Bros. Advisors LP (the “Adviser”), Baker Bros. Advisors (GP) LLC (the “Adviser GP”), Julian C. Baker and Felix J. Baker (collectively, the “Reporting Persons”). Except as supplemented herein, such statements, as heretofore amended and supplemented, remain in full force and effect.

 

The Adviser GP is the sole general partner of the Adviser. Pursuant to management agreements, as amended, among the Adviser, Baker Brothers Life Sciences, L.P. (“Life Sciences”) and 667, L.P. (“667”, and together with Life Sciences, the “Funds”), and their respective general partners, the Funds’ respective general partners relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds, and thus the Adviser has complete and unlimited discretion and authority with respect to the Funds’ investments and voting power over investments.

 

All capitalized terms contained herein but not otherwise defined shall have the meanings ascribed to such terms in the Schedule 13D, as amended. Information given in response to each item shall be deemed incorporated by reference in all other items, as applicable.

 

Item 3.Source and Amount of Funds or Other Consideration

 

The disclosure regarding sales in Item 5(c) below is incorporated herein by reference.

 

Item 4.Purpose of the Transaction.

 

Item 4 of Schedule 13D is supplemented and amended, as the case may be, as follows:

 

The disclosure in Item 3 above is incorporated herein by reference.

 

The Funds hold securities of the Issuer for investment purposes. The Reporting Persons or their affiliates may dispose of additional securities or purchase securities in varying amounts and at varying times depending upon the Reporting Persons’ continuing assessments of pertinent factors, including the availability of Ordinary Shares or other securities for purchase at particular price levels, the business prospects of the Issuer, other business investment opportunities, economic conditions, stock market conditions, money market conditions, the attitudes and actions of the Board and management of the Issuer, the availability and nature of opportunities to dispose of securities of the Issuer and other plans and requirements of the particular entities. The Reporting Persons may discuss items of mutual interest with the Issuer, which could include items in subparagraphs (a) through (j) of Item 4 of Schedule 13D.

 

Depending upon their assessments of the above factors, the Reporting Persons or their affiliates may change their present intentions as stated above and may make suggestions to the management of the Issuer regarding corporate financing and strategy, and may acquire or dispose of securities of the Issuer (by means of open market purchases, privately negotiated purchases, or otherwise).

 

Except as otherwise disclosed herein, at the present time, the Reporting Persons do not have any plans or proposals with respect to any extraordinary corporate transaction involving the Issuer including, without limitation, those matters described in subparagraphs (a) through (j) of Item 4 of Schedule 13D.

 

Item 5.Interest in Securities of the Issuer.

 

(a) and (b) Items 7 through 11 and 13 of each of the cover pages of this Amendment No. 1 are incorporated herein by reference. Set forth below is the aggregate number of Ordinary Shares of the Issuer directly held by each of the Funds, including Ordinary Shares owned through American Depositary Shares (“ADS”) held by each of the Funds, and the percentage of the Issuer’s outstanding Ordinary Shares such holdings represent. Each American Depositary Share represents one Ordinary Shares of the Issuer. The information set forth below is based upon 17,940,035 Ordinary Shares outstanding as of May 31, 2018 as reported by the Issuer. Such percentage figures are calculated in accordance with Rule 13d-3 under the Securities Exchange Act of 1934, as amended.

 

 

 

CUSIP No.  29604W108   Page   7   of   9   Pages

 

 

Holder 

Number of

Ordinary Shares

we own or have

the right to

acquire within 60

days

  

 

 

 

Percent of

Class

Outstanding

 
667, L.P.   308,518    1.7%
Baker Brothers Life Sciences, L.P.   2,777,451    15.5%
Total   3,085,969    17.2%

 

The Adviser GP, Felix J. Baker and Julian C. Baker as principals of the Adviser GP, and the Adviser may be deemed to be beneficial owners of securities of the Issuer directly held by the Funds, and may be deemed to have the power to vote or direct the vote of and the power to dispose or direct the disposition of such securities.

 

The Reporting Persons disclaim beneficial ownership of the securities of the Issuer held by each of the Funds, and this Amendment No. 1 shall not be deemed an admission that the Reporting Persons are the beneficial owners of such securities for purposes of Section 13(d) or for any other purpose, except to the extent that any such Reporting Person actually exercises voting or dispositive power with respect to such securities.

 

(c) The following transactions in the Issuer’s Ordinary Shares and ADS were effected by the Funds noted below during the sixty days preceding the filing of this statement. Except as disclosed herein, none of the Reporting Persons has effected any other transaction in the securities of the Issuer during the past 60 days.

 

Name Date Number of Shares Share Class  Transaction   Price per Share  Footnotes
667, L.P. 6/28/2018                         27,888 Ordinary  Sale  € 9.6718 1
Baker Brothers Life Sciences, L.P.  6/28/2018                      252,616 Ordinary  Sale  € 9.6718 1
667, L.P. 6/28/2018                                 10 ADS  Sale  $ 11.0000  
Baker Brothers Life Sciences, L.P.  6/28/2018                                 90 ADS  Sale  $ 11.0000  
667, L.P. 6/29/2018                      149,726 Ordinary  Sale  € 9.6000  
Baker Brothers Life Sciences, L.P.  6/29/2018                   1,373,065 Ordinary  Sale  € 9.6000  
667, L.P. 6/29/2018                               489 Ordinary  Sale  € 9.8315 2
Baker Brothers Life Sciences, L.P.  6/29/2018                           4,484 Ordinary  Sale  € 9.8315 2
667, L.P. 6/29/2018                               400 ADS  Sale  $ 11.1958 3
Baker Brothers Life Sciences, L.P.  6/29/2018                           3,600 ADS  Sale  $ 11.1958 3

 

(1)The reported price is a weighted average price. These shares were traded in multiple transactions at prices ranging from €9.65 to €9.91. The Reporting Persons undertake to provide the staff of the Securities and Exchange Commission (the “Staff”), upon request, full information regarding the number of shares traded at each separate price within the ranges set forth in this footnote.
(2)The reported price is a weighted average price. These shares were traded in multiple transactions at prices ranging from €9.75 to €9.96. The Reporting Persons undertake to provide the Staff, upon request, full information regarding the number of shares traded at each separate price within the ranges set forth in this footnote.
(3)The reported price is a weighted average price. These shares were traded in multiple transactions at prices ranging from $11.17 to $11.20. The Reporting Persons undertake to provide the Staff, upon request, full information regarding the number of shares traded at each separate price within the ranges set forth in this footnote.

 

 

 

CUSIP No.  29604W108   Page   8   of   9   Pages

 

 

(d) Certain securities of the Issuer are held directly by 667, a limited partnership the sole general partner of which is Baker Biotech Capital, L.P., a limited partnership the sole general partner of which is Baker Biotech Capital (GP), LLC. Julian C. Baker and Felix J. Baker are the controlling members of Baker Biotech Capital (GP), LLC.

 

Certain securities of the Issuer are held directly by Life Sciences, a limited partnership the sole general partner of which is Baker Brothers Life Sciences Capital, L.P., a limited partnership the sole general partner of which is Baker Brothers Life Sciences Capital (GP), LLC. Julian C. Baker and Felix J. Baker are the controlling members of Baker Brothers Life Sciences Capital (GP), LLC.

 

(e) Not applicable.

 

 

 

CUSIP No.  29604W108   Page   9   of   9   Pages

 

 

SIGNATURE

 

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

 

Dated: July 2, 2018

 

  BAKER BROS. ADVISORS LP
   
  By:  Baker Bros. Advisors (GP) LLC, its general partner
     
     
  By: /s/ Scott L. Lessing
    Name: Scott L. Lessing
Title: President
     
     
  BAKER BROS. ADVISORS (GP) LLC
     
     
  By: /s/ Scott L. Lessing
    Name: Scott L. Lessing
Title: President
     
     
  /s/ Julian C. Baker
  Julian C. Baker
     
     
  /s/ Felix J. Baker
  Felix J. Baker